• Quality Control
  
  
• Purity
  
  
• Enzyme Program
  
  
• Enzyme Specifications
  
  
• Coenzyme Program
  
  
• Coenzyme Specifications
  

OYC International, Inc.
300 Brickstone Square
Suite 1008
Andover MA, 01810
USA
Phone: 978-470-1980
Fax: 978-409-6282

Tech Information

Do you have any technical questions or difficulty to use our products? Do you need a technical support? Please let us help you solve the problem. Click here to send your question to our tachical staff via email. We will help you solve the problem as soon as possible.

Quality Control
Oriental Yeast, Co., Ltd. is ISO 9001 certified. Quality control programs are established in our Biochemical Research & Development Center in Osaka, Japan. All shipments of our enzymes, coenzymes and substrates include complete analytical data based on Oriental Yeast's specifications.

Purity
We believe our products to be of the highest purity commercially available. All products are purified not only by normal crystallization and lyophilization, but also by column chromatography and our exclusive and unique hydrogen bonding chromatography. This combination of extensive purification and exclusive H-bonding chromatography, developed by the Oriental Yeast Company's technical staff, assures you that you will be receiving materials of the same consistent quality, to assure trouble free performance.

Enzyme Program
Many years and countless dedicated hours of laboratory effort have gone into the development of the large-scale enzyme production techniques currently in use at our facilities. New isolation and production techniques are constantly being developed at the Oriental Yeast biochemical R&D Center. Direction for these continuing developments is responsive to the expanding areas of enzyme technology in the clinical diagnostics field.

As a result of our innovative and unique production systems, we are able to supply highly purified enzymes with high specific activity as well as reduced levels of contaminants.

In addition, our substantial efforts in the basic research fields of enzymology and enzyme production allow us to offer custom preparations based upon your particular requirements. This is only one of the many benefits provided by our "total" approach to the enzyme field. We will continue to strive to make our products the best available in the world.

Enzyme Specifications
Enzyme purity is determined to be at Contaminant levels are expressed as a percentage of the specific activity of the particular enzyme. Minimum activity required for each enzyme with maximum tolerable limits for contaminants are established for its presumed use. Recognizing the need for quality enzymes, we guarantee that levels of contaminants analyzed on each product will be lower than in our standard specifications.

Coenzyme Program
The care and dedication used in producing our products is further exemplified by the high quality of our coenzymes. The use of these materials in diagnostics as well as a wide variety of biochemical research fields has grown dramatically. This growth is largely due to the increased use of spectro- and fluoro-photometric methodologies which rely on the measurement of changes in the various techniques include increased speed, accuracy and relative ease of performance together with greater sensitivity and specificity.

We have pioneered the technology for removal of inhibitory substances from coenzymes, thus reducing the potential for competitive and inhibitory effects interfering with the course of a reaction.

We are pleased to offer a supply program which offers NAD+, NADH, NADP+ and NADPH that are virtually free of trace impurities.

These products are intended solely for research and manufacturing use. No product is offered for drug. Food, food additive or clinical use in humans.

Coenzyme Specifications
Coenzyme product specifications are derived from the publication "Specifications and Criteria for Biochemical Compounds" published by the National Academy of Science-National Research Council, Washington D.C.

Purity specifications are expressed in percent with reference to the molecular extinction coefficients in the UV spectra as well as by enzymatic assay.

Additional criteria for the purity of reduced coenzymes exists in their characteristic absorbance ratio of A(340nm, red)/A(260nm, red). Even for the oxidized coenzymes this ratio, calculated after reduction by a specific enzyme, is an important index of purity.

If this ratio is below the theoretical value of 0.43, there are impurities of other nucleotides or there is coenzyme degradation.

Other spectral ratio A250/A260 and A280/A260 are also used as characteristics of purity.